This is the age you should treat children for peanut allergies, researchers say
Research out of the University of British Columbia is giving more insight into a treatment designed to help young children overcome peanut allergies.
In 2019, researchers demonstrated that a treatment called oral immunotherapy was successful in treating peanut allergies in preschool-aged children.
They now say the earlier the treatment is given, the better the outcome will be.
"This treatment is affordable, very safe and highly effective, particularly if we can get the treatment going before the infant is 12 months old," says the study's senior author Dr. Edmond Chan in a news release.
The study, published in the Journal of Allergy and Clinical Immunology: In Practice, focused on infants under 12 months old and revealed oral immunotherapy is safer and more effective for this age group than it is for toddlers and older pre-schoolers.
According to Chan, oral immunotherapy is "a treatment protocol in which a patient consumes small amounts of the allergenic food — in this case, peanut flour — with the dose gradually increased to a determined maximum amount."
The goal is to desensitize the child until they're able to consume a full serving of peanut protein without it triggering a dangerous reaction.
The research suggests that children must continue to eat peanut products on a regular basis long-term, in order to sustain their immunity.
Throughout the study, a group of children visited a pediatric allergist every two weeks to receive their peanut dose. Parents were also told to provide the same daily dose at home between clinic visits. After eight to 11 visits, researchers found the children had built up to a "maintenance dose" of 300 milligrams of peanut protein, which is the equivalent of about 1.3 grams of peanuts.
They found that 42 infants completed the build-up period, plus one year of maintenance dosing.
"At the end of it, none of them had more than a mild reaction to a 4,000-milligram dose of peanut protein, compared to 7.7 per cent of the children aged one to five who completed the protocol," the study says.
Seven infants dropped out of the study, with four experiencing reactions beyond mild. Researchers say none of the infants required epinephrine injections as a result.
The study also found during initial testing that only 33.9 per cent of infants had a reaction beyond mild, compared to 53.7 per cent of children aged one through five.
"Despite infants showing the best safety, we were still very satisfied with the safety of this treatment for older pre-schoolers. The risk of a severe reaction is much lower than it is for school-age kids," says Chan.
"Many of the interventions we use in medicine, such as medications or surgical procedures, carry a small amount of risk that is outweighed by the benefit. If this treatment is performed by well-trained allergists and clinicians then I'm really comfortable with the risk. It's actually very safe."
When it comes to long-term effectiveness, researchers say the treatment worked "equally well" for both age groups.
"After a year of one peanut per day, approximately 80 per cent of the children had developed a tolerance for 4,000 milligrams of peanut protein one sitting," the study says.
That's the equivalent of about 15 peanuts.
Chan suggests that parents introduce foods like peanut butter or peanut flour to children around six months of age, to help prevent peanut allergies when they get older.
The head of allergy and immunology in UBC's department of pediatrics at the BC Children's Hospital Research Institute, Chan has embraced oral immunotherapy in his own clinical practice.
His research will be used to inform future clinical practice guidelines, the study says.
CTVNews.ca Top Stories
More than 115 cases of eye damage reported in Ontario after solar eclipse
More than 115 people who viewed the solar eclipse in Ontario earlier this month experienced eye damage after the event, according to eye doctors in the province.
Last letters of pioneering climber who died on Everest reveal dark side of mountaineering
George Mallory is renowned for being one of the first British mountaineers to attempt to scale the dizzying heights of Mount Everest during the 1920s. Nearly a century later, newly digitized letters shed light on Mallory’s hopes and fears about ascending Everest.
Toxic testing standoff: Family leaves house over air quality
A Sherwood Park family says their new house is uninhabitable. The McNaughton's say they were forced to leave the house after living there for only a week because contaminants inside made it difficult to breathe.
Decoy bear used to catch man who illegally killed a grizzly, B.C. conservation officers say
A man has been handed a lengthy hunting ban and fined thousands of dollars for illegally killing a grizzly bear, B.C. conservation officers say.
B.C. seeks ban on public drug use, dialing back decriminalization
The B.C. NDP has asked the federal government to recriminalize public drug use, marking a major shift in the province's approach to addressing the deadly overdose crisis.
Loud boom in Hamilton caused by propane tank, police say
A loud explosion was heard across Hamilton on Friday after a propane tank was accidentally destroyed and detonated at a local scrap metal yard, police say.
Sophie Gregoire Trudeau on navigating post-political life, co-parenting and freedom
Sophie Gregoire Trudeau says there is 'still so much love' between her and Prime Minister Justin Trudeau, as they navigate their post-separation relationship co-parenting their three children.
An emergency slide falls off a Delta Air Lines plane, forcing pilots to return to JFK in New York
An emergency slide fell off a Delta Air Lines jetliner shortly after takeoff Friday from New York, and pilots who felt a vibration in the plane circled back to land safely at JFK Airport.
OPP responds to apparent video of officer supporting anti-Trudeau government protestors
The Ontario Provincial Police (OPP) says it's investigating an interaction between a uniformed officer and anti-Trudeau government protestors after a video circulated on social media.